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Terminus Peptides
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  • 55 compound profiles, every source cited
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Research profile · Combination

Lipo-C

Also known as Lipotropic combination, MIC injection

Not assessed — evidence level 0 of 4: Evidence not yet assessedUnlicensed — UK regulatory status: Unlicensed medicinal product (UK)

Overview

A compounded mixture with no fixed formula, typically containing two substances that are prescription-only as injectables.

Category
Combination
Highest evidence level identified
Evidence not yet assessed
Last scientifically reviewed
20 August 2026
Last regulatory review
20 August 2026

Mechanism under investigation

Lipo-C is a name applied to compounded injectable mixtures, not a defined product. Formulations usually centre on methionine, inositol and choline — collectively abbreviated MIC — and commonly add L-carnitine and vitamin B12. Choline and methionine have genuine roles in hepatic lipid handling, which is where the term lipotropic originates, but a role in normal metabolism is not evidence that injecting the substance reduces body fat. The composition and the concentrations vary between preparations, so no single mechanism can be described for the mixture.

Research areas

  • Compounded preparations

These are fields in which the compound has been investigated. Listing a field is not a statement that anything was demonstrated within it.

Current evidence

In-vitro evidence

Cells, tissues or biochemical systems outside a living organism.

The individual nutrients are well studied in metabolic biochemistry. Nothing addresses the injectable mixture.

Animal evidence

Studies in living non-human animals.

None for the mixture.

Human observational evidence

Studies observing people without assigning an intervention.

None for the mixture.

Clinical-trial evidence

Studies assigning an intervention to human participants.

None. A targeted search for controlled studies of methionine, inositol and choline injections for weight loss or fat reduction returned no relevant trial. The retrieved literature concerns these nutrients in unrelated metabolic contexts — liver disease, animal nutrition — not injectable formulations for body composition. National weight-management guidance does not include lipotropic injections.

Study limitations

  • There is no standardised composition. Two vials labelled identically may differ substantially in what they contain and at what strength, so no result could be reproduced even in principle and no claim can transfer between preparations.
  • No clinical trial evidence exists for the mixture as a weight-loss or fat-reduction intervention.
  • A substance having a role in fat metabolism is not evidence that injecting it reduces body fat. That inference is the whole basis of the category and it has not been tested.
  • Typical formulations contain vitamin B12 and L-carnitine. Both are prescription-only medicines in the UK as injectables, which the mixture does not change.

UK regulatory context

Unlicensed medicinal product (UK)

A product meeting the definition of a medicinal product but holding no UK marketing authorisation.

Source: The Human Medicines Regulations 2012, regulation 46 — prohibition on sale or supply of an unauthorised medicinal product (opens legislation.gov.uk in a new tab) (legislation.gov.uk)

Regulatory classification is jurisdiction-specific. A compound authorised elsewhere is not thereby authorised in the UK, and a supplier’s description of a substance does not determine how it is classified in law. See safety and regulation for the framework and the authoritative sources.

Safety and interpretation

No safety data exist for the mixture. Because the formula is not fixed, a purchaser cannot know what is in a given vial, at what concentration, or whether it is sterile — and there is no marketing authorisation behind any of it, so no regulator has assessed identity, purity or sterility. The individual nutrients are unremarkable in the diet; that says nothing about injecting them in unverified combinations and quantities. The constituents that are prescription-only as injectables are so classified for reasons that do not lapse when they are mixed with others.

References